breseq  version 0.35.4  revision f352f80f4bc9
mutation predictions | marginal predictions | summary statistics | genome diff | command line log

Predicted mutations
evidence position mutation annotation gene description
RA 7,713 C→A A83S (GCT→TCT)  yaaJ ← putative transporter YaaJ
RA 31,527 C→A F237L (TTC→TTA)  carB → carbamoyl phosphate synthetase subunit beta
RA 35,400 C→A D255Y (GAT→TAT)  caiD ← crotonobetainyl‑CoA hydratase
RA 51,892 G→T A180D (GCC→GAC)  rsmA ← 16S rRNA m(6)2A1518,m(6)2A1519 dimethyltransferase
RA 80,367 C→A M166I (ATG→ATT)  leuC ← 3‑isopropylmalate dehydratase subunit LeuC
RA 83,714 C→A intergenic (‑6/‑654) leuL ← / → leuO leu operon leader peptide/DNA‑binding transcriptional dual regulator LeuO
RA 92,024 G→T P204P (CCG→CCT)  ftsI → peptidoglycan DD‑transpeptidase FtsI
RA 94,294 G→T A377S (GCG→TCG)  murE → UDP‑N‑acetylmuramoyl‑L‑alanyl‑D‑glutamate‑‑2, 6‑diaminopimelate ligase
RA 102,290 C→A L20M (CTG→ATG)  ddlB → D‑alanine‑‑D‑alanine ligase B
RA 131,516 C→A intergenic (‑256/‑99) yacH ← / → acnB DUF3300 domain‑containing protein YacH/hypothetical protein
RA 131,569 G→T intergenic (‑309/‑46) yacH ← / → acnB DUF3300 domain‑containing protein YacH/hypothetical protein
RA 147,151 G→T D62Y (GAC→TAC)  rpnC → recombination‑promoting nuclease RpnC
RA 150,831 G→T S41S (TCC→TCA)  yadC ← fimbrial tip‑adhesin YadC
RA 155,025 G→T I134I (ATC→ATA)  htrE ← putative fimbrial usher protein HtrE
RA 157,851 A→G F426L (TTC→CTC)  pcnB ← poly(A) polymerase I
RA 163,722 G→T G540C (GGC→TGC)  hrpB → putative ATP‑dependent RNA helicase HrpB
RA 171,824 G→T A121A (GCG→GCT)  fhuB → iron(III) hydroxamate ABC transporter membrane subunit
RA 177,462 G→T P55T (CCG→ACG)  yadS ← conserved inner membrane protein YadS
RA 205,377 G→T L84L (CTG→CTT)  dnaE → DNA polymerase III subunit alpha
RA 214,351 C→A Q21K (CAG→AAG)  yaeQ → uncharacterized protein YaeQ
RA 230,858 G→T L8L (CTC→CTA)  yafC ← putative LysR family transcriptional regulator YafC
RA 233,752 C→A K68N (AAG→AAT)  mltD ← membrane‑bound lytic murein transglycosylase D
RA 235,184 G→T L123L (CTG→CTT)  yafS → putative S‑adenosyl‑L‑methionine‑dependent methyltransferase
RA 237,429 C→A A32D (GCT→GAT)  yafT → lipoprotein YafT
RA 238,152 G→A intergenic (+32/+105) yafT → / ← ykfM lipoprotein YafT/uncharacterized protein YkfM
RA 244,109 G→T E189D (GAG→GAT)  lpcA → D‑sedoheptulose 7‑phosphate isomerase
RA 248,985 G→T pseudogene (1086/1713 nt) lfhA ← flagellar system protein, promoterless fragment
MC JC 257,908 Δ776 bp insB9–[crl] insB9, insA9, [crl]
RA 269,189 G→T intergenic (‑229/+100) ykfA ← / ← perR CP4‑6 prophage; putative GTP‑binding protein YkfA/putative transcriptional regulator PerR
RA 269,754 G→T L143L (CTC→CTA)  perR ← putative transcriptional regulator PerR
RA 271,571 G→T R323R (CGG→CGT)  insI‑1 → IS30 transposase
RA 281,031 C→A G318V (GGG→GTG)  yagA ← CP4‑6 prophage; integrase core domain‑containing protein YagA
RA 283,350 C→A A50A (GCC→GCA)  yagF → CP4‑6 prophage; D‑xylonate dehydratase
RA 284,596 G→T V466L (GTA→TTA)  yagF → CP4‑6 prophage; D‑xylonate dehydratase
RA 286,228 C→A G278G (GGC→GGA)  yagG → putative D‑xylonate transporter YagG
RA 286,452 G→T S353I (AGC→ATC)  yagG → putative D‑xylonate transporter YagG
RA 287,001 C→A G71G (GGC→GGA)  yagH → CP4‑6 prophage; putative xylosidase/arabinosidase
RA 293,471 C→A E150* (GAG→TAG)  yagL ← CP4‑6 prophage; resolvase‑like catalytic domain‑containing protein YagL
RA 305,693 C→A L375L (CTG→CTT)  ecpD ← fimbrial adhesin EcpD
RA 308,482 G→T A284D (GCC→GAC)  ecpC ← putative fimbrial usher protein EcpC
RA 340,879 G→T E239* (GAA→TAA)  yahI → carbamate kinase‑like protein YahI
RA 353,810 C→A P369T (CCG→ACG)  prpE → propionyl‑CoA synthetase
RA 354,948 G→A Q9Q (CAG→CAA)  codB → cytosine transporter
RA 364,437 G→T H623Q (CAC→CAA)  lacZ ← beta‑galactosidase
RA 368,563 C→A intergenic (‑143/‑48) mhpR ← / → mhpA DNA‑binding transcriptional activator MhpR/putative 3‑(3‑hydroxyphenyl)propanoate/3‑hydroxycinnamate hydroxylase
RA 380,146 C→A G233C (GGT→TGT)  yaiO ← outer membrane protein YaiO
RA 390,146 C→A intergenic (‑419/‑105) hemB ← / → yaiT porphobilinogen synthase/putative autotransporter YaiT
RA 402,172 G→T L142L (CTG→CTT)  phoA → alkaline phosphatase
RA 415,950 C→A V335L (GTA→TTA)  sbcD ← ATP dependent, structure specific DNA nuclease ‑ SbcD subunit
RA 429,195 G→T A517S (GCG→TCG)  secD → Sec translocon accessory complex subunit SecD
RA 429,482 G→T K612N (AAG→AAT)  secD → Sec translocon accessory complex subunit SecD
RA 431,143 C→A G291C (GGT→TGT)  tsx ← nucleoside‑specific channel‑forming protein Tsx
RA 434,183 C→A R243R (CGC→CGA)  ribD → fused diaminohydroxyphosphoribosylaminopyrimidine deaminase/5‑amino‑6‑(5‑phosphoribosylamino)uracil reductase
RA 436,977 C→A P130Q (CCG→CAG)  pgpA → phosphatidylglycerophosphatase A
RA 444,851 C→A Q57K (CAG→AAG)  yajQ → nucleotide binding protein
RA 453,438 C→A Q36H (CAG→CAT)  ampG ← muropeptide:H(+) symporter
RA 453,594 G→T R192S (CGT→AGT)  yajG ← putative lipoprotein YajG
RA 459,610 C→A L241L (CTC→CTA)  lon → Lon protease
RA 483,348 G→T F352L (TTC→TTA)  acrB ← multidrug efflux pump RND permease AcrB
RA 485,860 C→A L34M (CTG→ATG)  acrR → DNA‑binding transcriptional repressor AcrR
RA 495,508 C→A A130E (GCG→GAG)  htpG → chaperone protein HtpG
RA 500,138 G→T G5V (GGT→GTT)  gsk → inosine/guanosine kinase
RA 512,156 C→A A172A (GCC→GCA)  glsA → glutaminase 1
RA 515,074 G→T R234S (CGC→AGC)  qmcA ← PHB domain‑containing protein
RA 524,757 G→T L499L (CTG→CTT)  rhsD → protein RhsD
RA 534,093 G→T G60C (GGT→TGT)  gcl → glyoxylate carboligase
RA 537,063 G→T G160C (GGC→TGC)  glxR → tartronate semialdehyde reductase 2
RA 548,783 G→T D143Y (GAT→TAT)  ylbE → DUF1116 domain‑containing protein YlbE
RA 566,245 G→T pseudogene (117/264 nt) exoD ← DLP12 prophage; putative exonuclease ExoD
RA 586,374 G→T L179I (CTC→ATC)  envY ← DNA‑binding transcriptional activator EnvY
RA 601,449 C→A I912I (ATC→ATA)  cusA → copper/silver export system RND permease
RA 602,118 C→A P54T (CCG→ACG)  pheP → phenylalanine:H(+) symporter PheP
RA 605,314 G→T S37R (AGC→AGA)  nfsB ← NAD(P)H nitroreductase NfsB
RA 607,689 G→T intergenic (‑306/‑45) ybdK ← / → sokE carboxylate‑amine ligase/small RNA SokE
RA 620,401 G→T A263E (GCA→GAA)  fepG ← ferric enterobactin ABC transporter membrane subunit FepG
RA 633,676 C→A Q31K (CAG→AAG)  ybdL → methionine‑oxo‑acid transaminase, PLP‑dependent
RA 637,053 G→T T189N (ACT→AAT)  ybdO ← putative LysR family DNA‑binding transcriptional regulator YbdO
RA 654,798 C→A A391S (GCG→TCG)  dcuC ← anaerobic C4‑dicarboxylate transporter DcuC
RA 660,075 C→A D48Y (GAC→TAC)  lipA ← lipoyl synthase
RA 660,409 C→A intergenic (‑193/+16) lipA ← / ← ybeF lipoyl synthase/putative LysR‑type DNA‑binding transcriptional regulator YbeF
RA 683,821 G→T H198N (CAC→AAC)  rihA ← pyrimidine‑specific ribonucleoside hydrolase RihA
RA 709,281 G→T K316N (AAG→AAT)  chiP → chitobiose outer membrane channel
RA 710,592 G→T R19S (CGT→AGT)  fur ← DNA‑binding transcriptional dual regulator Fur
RA 711,133 C→A P111P (CCG→CCT)  fldA ← flavodoxin 1
RA 720,218 G→T V81V (GTC→GTA)  speF ← ornithine decarboxylase, degradative
RA 729,562 C→A intergenic (+222/‑21) ybfA → / → rhsC DUF2517 domain‑containing protein YbfA/rhs element protein RhsC
RA 729,808 C→A R76S (CGC→AGC)  rhsC → rhs element protein RhsC
RA 731,365 G→T E595* (GAA→TAA)  rhsC → rhs element protein RhsC
RA 742,050 C→A M169I (ATG→ATT)  dtpD ← dipeptide:H(+) symporter DtpD
RA 744,002 C→A P137Q (CCG→CAG)  pxpB → 5‑oxoprolinase component B
RA 747,861 G→T intergenic (‑92/+60) abrB ← / ← ybgO putative regulator/putative fimbrial protein YbgO
RA 753,875 G→T F198L (TTC→TTA)  gltA ← citrate synthase
RA 764,442 C→A A88E (GCA→GAA)  sucD → succinyl‑CoA synthetase subunit alpha
RA 766,404 G→T A141S (GCG→TCG)  mngA → 2‑O‑alpha‑mannosyl‑D‑glycerate specific PTS enzyme II
RA 782,216 G→T M44I (ATG→ATT)  nadA → quinolinate synthase
RA 796,755 G→T G68C (GGT→TGT)  modC → molybdate ABC transporter ATP binding subunit
RA 801,271 C→A T171T (ACC→ACA)  ybhH → putative isomerase YbhH
RA 803,877 G→T P125P (CCG→CCT)  ybhJ → putative hydratase YbhJ
RA 805,442 C→A A647E (GCG→GAG)  ybhJ → putative hydratase YbhJ
RA 812,883 C→A P205H (CCC→CAC)  bioD → dethiobiotin synthetase
RA 822,058 G→T T147T (ACC→ACA)  ybhN ← conserved inner membrane protein YbhN
RA 822,835 G→C T302R (ACA→AGA)  clsB ← cardiolipin synthase B
RA 832,481 G→T A157D (GCT→GAT)  ybiA ← N‑glycosidase YbiA
RA 839,929 C→A V535F (GTT→TTT)  fiu ← putative iron siderophore outer membrane transporter
RA 842,492 C→A A54E (GCG→GAG)  rlmF → 23S rRNA m(6)A1618 methyltransferase
RA 850,720 G→T G91C (GGT→TGT)  ompX → outer membrane protein X
RA 851,280 C→A D440Y (GAT→TAT)  opgE ← phosphoethanolamine transferase
RA 889,923 A→G intergenic (‑104/‑166) ybjL ← / → ybjM putative transport protein YbjL/putative inner membrane protein
RA 895,847 C→A S286* (TCG→TAG)  potG → putrescine ABC transporter ATP binding subunit
RA 929,362 C→A R534L (CGC→CTC)  cydD ← glutathione/L‑cysteine ABC exporter subunit CydD
RA 931,944 G→T T36N (ACC→AAC)  trxB ← thioredoxin reductase
RA 938,650 G→T A219A (GCG→GCT)  rarA → recombination factor
RA 948,861 G→T I236I (ATC→ATA)  ycaN ← putative LysR‑type transcriptional regulator YcaN
RA 951,898 C→A G553C (GGT→TGT)  pflB ← pyruvate formate‑lyase
RA 952,118 G→T R479R (CGC→CGA)  pflB ← pyruvate formate‑lyase
RA 953,891 C→A A192A (GCG→GCT)  focA ← formate channel FocA
RA 954,667 C→A intergenic (‑201/+205) focA ← / ← ycaO formate channel FocA/ribosomal protein S12 methylthiotransferase accessory factor YcaO
RA 958,963 G→T R51L (CGC→CTC)  aroA → 3‑phosphoshikimate 1‑carboxyvinyltransferase
RA 959,135 G→T L108L (CTG→CTT)  aroA → 3‑phosphoshikimate 1‑carboxyvinyltransferase
RA 960,051 C→A P414T (CCG→ACG)  aroA → 3‑phosphoshikimate 1‑carboxyvinyltransferase
RA 964,264 C→A intergenic (+152/‑56) ihfB → / → ycaI integration host factor subunit beta/conserved inner membrane protein YcaI
RA 982,472 G→T A476S (GCC→TCC)  ldtD → L,D‑transpeptidase LdtD
RA 990,842 G→T W74L (TGG→TTG)  pepN → aminopeptidase N
RA 1,005,609 G→T R281L (CGC→CTC)  pyrD → dihydroorotate dehydrogenase, type 2
RA 1,010,866 G→T V301V (GTG→GTT)  uup → ATP‑binding protein with possible role in replication
RA 1,011,436 G→T L491F (TTG→TTT)  uup → ATP‑binding protein with possible role in replication
RA 1,031,320 G→T A33A (GCC→GCA)  yccA ← modulator of FtsH protease
RA 1,035,812 C→A L15M (CTG→ATG)  hyaD → putative hydrogenase 1 maturation protease HyaD
RA 1,039,335 C→A L14M (CTG→ATG)  appB → cytochrome bd‑II ubiquinol oxidase subunit II
RA 1,050,622 G→A intergenic (+92/+341) insB‑4 → / ← cspH IS1 protein InsB/CspA family protein CspH
RA 1,061,110 G→T E619* (GAG→TAG)  torA → trimethylamine N‑oxide reductase 1
RA 1,072,686 C→A A60S (GCG→TCG)  rutB ← peroxyureidoacrylate/ureidoacrylate amidohydrolase
RA 1,090,550 C→A A580A (GCG→GCT)  pgaA ← partially deacetylated poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine outer membrane porin
RA 1,091,722 C→A E190* (GAG→TAG)  pgaA ← partially deacetylated poly‑beta‑1,6‑N‑acetyl‑D‑glucosamine outer membrane porin
RA 1,096,932 C→A intergenic (+103/+633) ycdU → / ← serX uncharacterized protein YcdU/tRNA‑Ser
RA 1,097,681 G→T intergenic (‑29/‑205) serX ← / → ghrA tRNA‑Ser/glyoxylate/hydroxypyruvate reductase A
RA 1,099,875 G→T R79L (CGT→CTT)  ycdY → chaperone protein YcdY
RA 1,101,564 G→T H41N (CAT→AAT)  csgG ← curli secretion channel
RA 1,102,321 G→T T74N (ACT→AAT)  csgE ← curli transport specificity factor
RA 1,102,882 G→T N105K (AAC→AAA)  csgD ← DNA‑binding transcriptional dual regulator CsgD
RA 1,104,052 G→T A34A (GCG→GCT)  csgB → curlin, minor subunit
RA 1,109,595 G→T M87I (ATG→ATT)  opgG → osmoregulated periplasmic glucans (OPGs) biosynthesis protein G
RA 1,111,156 G→T P98P (CCG→CCT)  opgH → osmoregulated periplasmic glucans (OPGs) biosynthesis protein H
RA 1,118,048 C→A Q143H (CAG→CAT)  yceI ← protein YceI
RA 1,118,680 C→A G123C (GGC→TGC)  yceJ ← putative cytochrome b561
RA 1,131,020 G→T M1M (ATG→ATT) † flgB → flagellar basal‑body rod protein FlgB
RA 1,133,946 C→A L49I (CTT→ATT)  flgF → flagellar basal‑body rod protein FlgF
RA 1,135,275 G→T G183W (GGG→TGG)  flgG → flagellar basal‑body rod protein FlgG
RA 1,139,017 G→T G214C (GGT→TGT)  flgK → flagellar hook‑filament junction protein 1
RA 1,183,490 G→T T44N (ACC→AAC)  potC ← spermidine preferential ABC transporter membrane subunit PotC
RA 1,192,119 C→A L171L (CTG→CTT)  hflD ← lysogenization regulator
RA 1,196,220 C→T H366H (CAC→CAT)  icd → isocitrate dehydrogenase
RA 1,196,232 C→T T370T (ACC→ACT)  icd → isocitrate dehydrogenase
RA 1,196,245 T→C L375M (TTA→CTG)  icd → isocitrate dehydrogenase
RA 1,196,247 A→G L375M (TTA→CTG)  icd → isocitrate dehydrogenase
RA 1,229,904 C→A S164I (AGC→ATC)  hlyE ← hemolysin E
RA 1,232,159 C→A A325D (GCT→GAT)  umuC → DNA polymerase V catalytic protein
RA 1,238,641 G→T M357I (ATG→ATT)  dadA → D‑amino acid dehydrogenase
RA 1,239,274 C→A G132G (GGC→GGA)  dadX → alanine racemase 2
RA 1,250,718 G→T P41T (CCT→ACT)  dhaK ← dihydroxyacetone kinase subunit K
RA 1,274,373 G→T W197L (TGG→TTG)  ychO → putative invasin YchO
RA 1,316,465 G→T A253E (GCG→GAG)  trpA ← tryptophan synthase subunit alpha
RA 1,319,732 G→T A19A (GCC→GCA)  trpC ← fused indole‑3‑glycerol phosphate synthase/phosphoribosylanthranilate isomerase
RA 1,320,760 G→T Q209K (CAG→AAG)  trpD ← anthranilate synthase subunit TrpD
RA 1,347,773 C→A E380D (GAG→GAT)  rnb ← RNase II
RA 1,350,622 C→A A140S (GCC→TCC)  fabI ← enoyl‑[acyl‑carrier‑protein] reductase
RA 1,351,219 C→A intergenic (‑180/+188) fabI ← / ← ycjD enoyl‑[acyl‑carrier‑protein] reductase/DUF559 domain‑containing protein YcjD
RA 1,359,414 C→A intergenic (‑73/+76) ymjE ← / ← puuA protein YmjE/glutamate‑putrescine ligase
RA 1,361,760 C→A P214H (CCT→CAT)  puuD → gamma‑glutamyl‑gamma‑aminobutyrate hydrolase
RA 1,364,669 C→A R146R (CGC→CGA)  puuB → gamma‑glutamylputrescine oxidase
RA 1,373,627 G→T G136C (GGC→TGC)  ycjO → putative ABC transporter membrane subunit YcjO
RA 1,389,683 G→T G252W (GGG→TGG)  ycjG → L‑Ala‑D/L‑Glu epimerase
RA 1,401,775 G→T intergenic (‑2/+35) abgT ← / ← abgB p‑aminobenzoyl glutamate:H(+) symporter/p‑aminobenzoyl‑glutamate hydrolase subunit B
RA 1,412,098 C→A G380W (GGG→TGG)  intR ← Rac prophage; putative integrase
RA 1,415,946 C→A G481W (GGG→TGG)  recE ← Rac prophage; exonuclease VIII, ds DNA exonuclease, 5' ‑‑> 3' specific
RA 1,439,233 C→A A518S (GCA→TCA)  ydbK ← putative pyruvate‑flavodoxin oxidoreductase
RA 1,440,658 C→A G43C (GGC→TGC)  ydbK ← putative pyruvate‑flavodoxin oxidoreductase
RA 1,459,527 G→T G158G (GGG→GGT)  paaH → 3‑hydroxyadipyl‑CoA dehydrogenase
RA 1,472,049 C→A pseudogene (1531/3495 nt) ydbA → putative outer membrane protein, N‑terminal fragment
RA 1,516,109 C→A P178T (CCG→ACG)  patD → gamma‑aminobutyraldehyde dehydrogenase
RA 1,536,036 G→T T194T (ACC→ACA)  narV ← nitrate reductase Z subunit gamma
RA 1,540,430 C→A G721C (GGC→TGC)  narZ ← nitrate reductase Z subunit alpha
RA 1,540,576 G→T A672D (GCC→GAC)  narZ ← nitrate reductase Z subunit alpha
RA 1,552,210 C→A intergenic (+219/+188) fdnI → / ← yddM formate dehydrogenase N subunit gamma/putative DNA‑binding transcriptional regulator YddM
RA 1,555,939 G→T H9N (CAT→AAT)  sra ← 30S ribosomal subunit protein S22
RA 1,611,118 C→A R246L (CGT→CTT)  dgcF ← putative diguanylate cyclase DgcF
RA 1,620,221 C→A intergenic (+14/+17) marB → / ← eamA multiple antibiotic resistance protein/cysteine/O‑acetylserine exporter EamA
RA 1,620,753 C→A V129L (GTG→TTG)  eamA ← cysteine/O‑acetylserine exporter EamA
RA 1,639,199 G→T A110D (GCC→GAC) 
P46T (CCG→ACG) 
rzpQ ←
rzoQ ←
Qin prophage; DUF2514 domain‑containing protein RzpQ
Qin prophage; putative lipoprotein RzoQ
RA 1,654,082 G→T P354T (CCG→ACG)  rspA ← mandelate racemase/muconate lactonizing enzyme family protein RspA
RA 1,656,007 G→T R67L (CGC→CTC)  ynfB → DUF1283 domain‑containing protein YnfB
RA 1,666,940 G→T L94I (CTC→ATC)  ynfK ← putative dethiobiotin synthetase
RA 1,668,590 C→A intergenic (‑26/+109) mlc ← / ← ynfL DNA‑binding transcriptional repressor Mlc/putative DNA‑binding transcriptional regulator
RA 1,672,861 C→G V97L (GTC→CTC)  mdtI ← multidrug/spermidine efflux pump membrane subunit MdtI
RA 1,678,604 G→T A60S (GCA→TCA)  ydgH → DUF1471 domain‑containing protein YdgH
RA 1,687,146 G→T P411Q (CCG→CAG)  fumA ← fumarase A
RA 1,700,171 C→A Q273K (CAA→AAA)  malX → PTS enzyme IIBC component MalX
RA 1,702,202 G→T intergenic (+73/‑31) malY → / → add negative regulator of MalT activity/cystathionine beta‑lyase/adenosine deaminase
RA 1,704,512 C→A intergenic (‑204/‑39) ydgJ ← / → blr putative oxidoreductase YdgJ/beta‑lactam resistance protein
RA 1,715,551 C→A P113P (CCG→CCT)  pdxY ← pyridoxal kinase 2
RA 1,721,115 G→T A31S (GCG→TCG)  ydhI → DUF1656 domain‑containing protein YdhI
RA 1,725,732 G→T R63R (CGC→CGA)  ydhL ← conserved protein YdhL
RA 1,731,633 C→G N849K (AAC→AAG)  lhr → putative ATP‑dependent helicase Lhr
RA 1,737,142 G→A A50V (GCA→GTA)  ydhP ← putative transporter YdhP
RA 1,737,816 C→A intergenic (‑271/‑28) ynhF ← / → purR stress response membrane protein YnhF/DNA‑binding transcriptional repressor PurR
RA 1,738,845 C→A G334G (GGC→GGA)  purR → DNA‑binding transcriptional repressor PurR
RA 1,748,651 G→T T507T (ACG→ACT)  ydhS → FAD/NAD(P) binding domain‑containing protein YdhS
RA 1,786,808 G→T P102H (CCT→CAT)  ppsA ← phosphoenolpyruvate synthetase
RA 1,810,978 G→T L15L (CTG→CTT)  tcyP → cystine/sulfocysteine:cation symporter
RA 1,815,884 C→A A673E (GCG→GAG)  katE → catalase II
RA 1,831,404 C→A Q193H (CAG→CAT)  astC ← succinylornithine transaminase
RA 1,833,808 C→A T136T (ACC→ACA)  ydjX → DedA family protein YdjX
RA 1,834,658 G→T P181P (CCG→CCT)  ydjY → 4Fe‑4S ferredoxin‑type domain‑containing protein YdjY
RA 1,843,481 G→T A371S (GCG→TCG)  gdhA → glutamate dehydrogenase
RA 1,844,764 G→T A36A (GCC→GCA)  ynjI ← DUF1266 domain‑containing protein YnjI
RA 1,853,608 C→A M124I (ATG→ATT)  ydjE ← putative transporter YdjE
RA 1,872,190 T→C F50F (TTT→TTC)  dgcJ → putative diguanylate cyclase DgcJ
JC JC 1,879,829 Δ1 bp :: IS186 (–) +6 bp :: Δ1 bp coding (115‑120/360 nt) yeaR ← DUF1971 domain‑containing protein YeaR
RA 1,885,920 C→A L26M (CTG→ATG)  yeaX → carnitine monooxygenase subunit YeaX
RA 1,901,553 C→A A11A (GCG→GCT)  yoaE ← putative inner membrane protein
RA 1,906,405 G→T P219Q (CCG→CAG)  rlmA ← 23S rRNA m(1)G745 methyltransferase
RA 1,909,124 C→A P67Q (CCG→CAG)  yobH → protein YobH
RA 1,909,663 G→T A146E (GCG→GAG)  kdgR ← DNA‑binding transcriptional repressor KdgR
RA 1,932,177 C→A A194S (GCG→TCG)  eda ← KHG/KDPG aldolase
RA 1,938,540 C→A R298S (CGT→AGT)  pykA → pyruvate kinase II
RA 1,942,365 C→A Q73H (CAG→CAT)  znuA ← Zn(2(+)) ABC transporter periplasmic binding protein
RA 1,947,067 C→A A104S (GCA→TCA)  ruvC ← crossover junction endodeoxyribonuclease RuvC
MC JC 1,978,503 Δ776 bp insB‑5–insA‑5 insB‑5, insA‑5
RA 1,994,191 C→A G172G (GGG→GGT)  uvrC ← excision nuclease subunit C
RA 1,998,875 C→T L202L (CTG→CTA)  dcyD ← D‑cysteine desulfhydrase
RA 2,004,452 C→A S194* (TCG→TAG)  fliD → flagellar filament capping protein
RA 2,017,968 C→A A8E (GCG→GAG)  fliJ → flagellar biosynthesis protein FliJ
RA 2,022,865 C→A L84M (CTG→ATG)  fliQ → flagellar biosynthesis protein FliQ
RA 2,028,701 C→A L222F (TTG→TTT)  yedI ← conserved inner membrane protein YedI
RA 2,029,806 G→T E90* (GAA→TAA)  yedA → putative transporter YedA
RA 2,037,957 G→T P66T (CCT→ACT)  hprS ← sensory histidine kinase HprS
RA 2,050,545 G→T G1870C (GGT→TGT)  yeeJ → inverse autotransporter adhesin
RA 2,068,788 C→A pseudogene (154/306 nt) yoeA → CP4‑44 prophage; TonB‑dependent receptor plug domain‑containing protein YoeA
RA 2,091,585 G→T P163P (CCG→CCT)  hisD → histidinal/histidinol dehydrogenase
RA 2,092,728 G→T G111C (GGC→TGC)  hisC → histidinol‑phosphate aminotransferase
RA 2,094,525 G→T G353V (GGA→GTA)  hisB → imidazoleglycerol‑phosphate dehydratase/histidinol‑phosphatase
RA 2,120,829 G→T T242T (ACC→ACA)  wcaJ ← undecaprenyl‑phosphate glucose phosphotransferase
RA 2,123,025 C→A intergenic (‑46/+59) cpsG ← / ← cpsB phosphomannomutase/mannose‑1‑phosphate guanylyltransferase
RA 2,126,359 C→A D278Y (GAT→TAT)  fcl ← GDP‑L‑fucose synthase
RA 2,136,902 G→T S114R (AGC→AGA)  wza ← outer membrane polysaccharide export protein Wza
RA 2,139,597 C→A intergenic (+112/+162) yegH → / ← asmA inner membrane protein YegH/putative assembly protein AsmA
RA 2,140,635 C→A S326S (TCG→TCT)  asmA ← putative assembly protein AsmA
RA 2,157,867 C→A L869M (CTG→ATG)  mdtB → multidrug efflux pump RND permease subunit MdtB
RA 2,160,183 G→T G600C (GGC→TGC)  mdtC → multidrug efflux pump RND permease subunit MdtC
RA 2,165,292 C→A S35* (TCA→TAA)  yegP → DUF1508 domain‑containing protein YegP
RA 2,173,363 Δ2 bp pseudogene (915‑916/1358 nt) gatC ← galactitol‑specific PTS enzyme IIC component
RA 2,180,084 G→T G422W (GGG→TGG)  yegT → putative transporter YegT
RA 2,185,030 C→A S91I (AGC→ATC)  thiM ← hydroxyethylthiazole kinase
RA 2,190,155 C→A Q252H (CAG→CAT)  yehB ← putative fimbrial usher protein YehB
RA 2,197,614 C→A intergenic (+316/‑2665) yehF → / → yehI putative protein YehF/DUF4132 domain‑containing protein YehI
RA 2,233,055 G→T G60C (GGC→TGC)  sanA → DUF218 domain‑containing protein SanA
RA 2,260,516 G→T L299I (CTC→ATC)  fruA ← fructose‑specific PTS multiphosphoryl transfer protein FruA
RA 2,267,177 C→A F311L (TTC→TTA)  yeiQ → putative dehydrogenase, NAD‑dependent
RA 2,267,575 C→A A444D (GCC→GAC)  yeiQ → putative dehydrogenase, NAD‑dependent
RA 2,280,276 C→A G70C (GGC→TGC)  rsuA ← 16S rRNA pseudouridine(516) synthase
RA 2,282,132 G→T G501C (GGC→TGC)  radD → putative DNA repair helicase RadD
RA 2,291,925 G→T G162G (GGC→GGA)  ccmH ← holocytochrome c synthetase ‑ thiol:disulfide oxidoreductase CcmH
RA 2,305,506 G→T Q417K (CAA→AAA)  mqo ← malate:quinone oxidoreductase
RA 2,307,377 C→A L413L (CTG→CTT)  yojI ← ABC transporter family protein/microcin J25 efflux protein
RA 2,308,412 C→A S68S (TCG→TCT)  yojI ← ABC transporter family protein/microcin J25 efflux protein
RA 2,313,744 C→A S86Y (TCC→TAC)  rcsD → RcsD phosphotransferase
RA 2,321,479 G→T R479R (CGG→CGT)  atoS → sensory histidine kinase AtoS
RA 2,323,977 G→T L177L (CTG→CTT)  atoD → acetyl‑CoA:acetoacetyl‑CoA transferase subunit alpha
RA 2,342,926 C→A G415V (GGC→GTC)  yfaL ← putative autotransporter adhesin YfaL
RA 2,348,571 C→A P20T (CCT→ACT)  yfaE → ferredoxin‑like diferric‑tyrosyl radical cofactor maintenance protein YfaE
RA 2,358,557 G→T P97T (CCG→ACG)  yfaU ← 2‑keto‑3‑deoxy‑L‑rhamnonate aldolase
RA 2,360,580 C→A G279C (GGC→TGC)  rhmD ← L‑rhamnonate dehydratase
RA 2,362,685 C→A A317S (GCC→TCC)  yfaY ← IPR008135 CinA family protein YfaY
RA 2,364,101 C→A G59C (GGT→TGT)  yfaZ ← putative porin YfaZ
RA 2,369,610 G→T P524P (CCG→CCT)  arnA → fused UDP‑4‑amino‑4‑deoxy‑L‑arabinose formyltransferase/UDP‑glucuronate dehydrogenase
RA 2,371,042 C→A S45S (TCC→TCA)  arnT → lipid IVA 4‑amino‑4‑deoxy‑L‑arabinosyltransferase
RA 2,373,188 G→T G99G (GGG→GGT)  arnF → undecaprenyl‑phosphate‑alpha‑L‑Ara4N flippase ‑ ArnF subunit
RA 2,378,088 C→A S391I (AGC→ATC)  menD ← 2‑succinyl‑5‑enolpyruvyl‑6‑hydroxy‑3‑ cyclohexene‑1‑carboxylate synthase
RA 2,379,773 C→A D291Y (GAT→TAT)  menF ← isochorismate synthase MenF
RA 2,381,441 G→T P35T (CCT→ACT)  elaA ← putative N‑acetyltransferase ElaA
RA 2,387,455 G→T intergenic (+18/+255) yfbM → / ← yfbN DUF1877 domain‑containing protein YfbM/uncharacterized protein YfbN
RA 2,392,703 C→A Q113H (CAG→CAT)  nuoM ← NADH:quinone oxidoreductase subunit M
RA 2,394,378 C→A L223L (CTG→CTT)  nuoL ← NADH:quinone oxidoreductase subunit L
RA 2,411,285 C→A R23I (AGA→ATA)  yfbS ← putative transporter YfbS
RA 2,412,050 G→T L14M (CTG→ATG)  hxpA ← hexitol phosphatase A
RA 2,421,126 G→T W169L (TGG→TTG)  yfcG → disulfide reductase
RA 2,422,882 C→A G220W (GGG→TGG)  rpnB ← recombination‑promoting nuclease RpnB
RA 2,424,291 G→T R73R (CGC→CGA)  hisP ← lysine/arginine/ornithine ABC transporter/histidine ABC transporter, ATP binding subunit
RA 2,437,347 C→A D169Y (GAT→TAT)  pdxB ← erythronate‑4‑phosphate dehydrogenase
RA 2,439,467 G→T I218I (ATC→ATA)  yfcJ ← putative transporter YfcJ
RA 2,443,681 C→A P640T (CCG→ACG)  mnmC → fused 5‑methylaminomethyl‑2‑thiouridine‑forming methyltransferase and FAD‑dependent demodification enzyme
RA 2,449,995 C→A A19S (GCT→TCT)  yfcO ← DUF2544 domain‑containing protein YfcO
RA 2,450,884 C→A V64V (GTG→GTT)  yfcQ ← putative fimbrial protein YfcQ
RA 2,484,593 G→T D74Y (GAT→TAT)  evgS → sensory histidine kinase EvgS
RA 2,489,823 C→A G122C (GGT→TGT)  yfdV ← putative transport protein YfdV
RA 2,493,524 G→T intergenic (‑270/+243) frc ← / ← yfdX formyl‑CoA transferase/protein YfdX
RA 2,499,366 C→A C232* (TGC→TGA)  ypdA → sensory histidine kinase YpdA
RA 2,505,238 C→A E104* (GAG→TAG)  ypdE ← broad‑specificity exoaminopeptidase
RA 2,509,514 C→A intergenic (‑88/‑116) glk ← / → yfeO glucokinase/putative transport protein YfeO
RA 2,518,871 C→A A20D (GCT→GAT)  yfeD → putative DNA‑binding transcriptional regulator YfeD
RA 2,523,024 G→T A321E (GCA→GAA)  xapB ← xanthosine:H(+) symporter XapB
RA 2,539,504 A→G V27A (GTG→GCG)  cysM ← cysteine synthase B
RA 2,540,607 G→T H70N (CAC→AAC)  cysA ← sulfate/thiosulfate ABC transporter ATP binding subunit
RA 2,543,931 C→A A231A (GCG→GCT)  ucpA ← putative oxidoreductase
RA 2,555,739 C→A intergenic (‑11/+2) eutK ← / ← eutL putative structural protein, ethanolamine utilization microcompartment/putative structural protein, ethanolamine utilization microcompartment
RA 2,560,851 G→T E199* (GAG→TAG)  yffL → CPZ‑55 prophage; uncharacterized protein YffL
RA 2,571,411 C→A G114V (GGC→GTC)  eutE ← putative aldehyde dehydrogenase, ethanolamine utilization protein
RA 2,587,746 G→T G51V (GGC→GTC)  acrD → multidrug efflux pump RND permease AcrD
RA 2,609,668 C→A P394P (CCC→CCA)  hyfG → hydrogenase 4 catalytic subunit HyfG
RA 2,611,383 C→A T226T (ACC→ACA)  hyfI → hydrogenase 4 catalytic subunit HyfI
RA 2,635,711 G→T P35Q (CCA→CAA)  yfgJ ← zinc ribbon domain‑containing protein YfgJ
RA 2,660,551 G→T A327A (GCC→GCA)  iscS ← cysteine desulfurase
RA 2,662,341 G→T intergenic (‑210/+242) iscR ← / ← trmJ DNA‑binding transcriptional dual regulator IscR/tRNA Cm32/Um32 methyltransferase
RA 2,667,286 G→T R187R (CGC→CGA)  hcaT ← putative 3‑phenylpropionate transporter
RA 2,667,603 G→T L82I (CTC→ATC)  hcaT ← putative 3‑phenylpropionate transporter
RA 2,670,155 G→T W375L (TGG→TTG)  hcaE → putative 3‑phenylpropionate/cinnamate dioxygenase subunit alpha
RA 2,672,017 G→T A265S (GCG→TCG)  hcaB → 2,3‑dihydroxy‑2,3‑dihydrophenylpropionate dehydrogenase
RA 2,675,353 C→A E137* (GAA→TAA)  yphC ← putative zinc‑binding dehydrogenase YphC
RA 2,677,008 C→A A452S (GCC→TCC)  yphE ← putative ABC transporter ATP‑binding protein YphE
RA 2,689,088 C→A R140L (CGC→CTC)  qseG ← outer membrane lipoprotein QseG
RA 2,694,508 C→A E346* (GAA→TAA)  purL ← phosphoribosylformylglycinamide synthetase
RA 2,695,621 C→A intergenic (‑78/‑180) purL ← / → mltF phosphoribosylformylglycinamide synthetase/membrane‑bound lytic murein transglycosylase F
RA 2,703,619 G→T P149T (CCA→ACA)  rnc ← RNase III
RA 2,708,988 C→A L139L (CTG→CTT)  rseA ← anti‑sigma factor
RA 2,714,194 C→A S433R (AGC→AGA)  srmB → ATP‑dependent RNA helicase SrmB
RA 2,720,344 C→A A131D (GCT→GAT)  patZ → peptidyl‑lysine acetyltransferase
RA 2,725,813 G→T intergenic (‑67/+256) kgtP ← / ← rrfG alpha‑ketoglutarate:H(+) symporter/5S ribosomal RNA
RA 2,739,856 C→A E72* (GAG→TAG)  tyrA ← fused chorismate mutase/prephenate dehydrogenase
RA 2,776,951 C→A C25* (TGC→TGA)  ypjJ → CP4‑57 prophage; DUF987 domain‑containing protein YpjJ
RA 2,791,581 C→A A103A (GCC→GCA)  gabD → NADP(+)‑dependent succinate‑semialdehyde dehydrogenase
RA 2,808,449 C→A pseudogene (134/1178 nt) ygaY → putative transporter YgaY, N‑terminal fragment
RA 2,813,757 C→A P381Q (CCG→CAG)  emrB → multidrug efflux pump membrane subunit EmrB
RA 2,821,852 G→T L54I (CTC→ATC)  alaS ← alanine‑‑tRNA ligase/DNA‑binding transcriptional repressor
RA 2,834,627 C→A P239Q (CCG→CAG)  norW → NADH:flavorubredoxin reductase
RA 2,847,236 G→T A59A (GCC→GCA)  hycD ← formate hydrogenlyase subunit HycD
RA 2,868,229 G→T G175G (GGC→GGA)  nlpD ← murein hydrolase activator NlpD
RA 2,889,937 G→T H55N (CAC→AAC)  cysI ← sulfite reductase, hemoprotein subunit
RA 2,891,477 G→T P141Q (CCA→CAA)  cysJ ← sulfite reductase, flavoprotein subunit
RA 2,896,462 C→A D32Y (GAT→TAT)  ygcR ← putative flavoprotein
RA 2,904,135 C→A intergenic (+761/+612) ygcE → / ← queE putative sugar kinase YgcE/putative 7‑carboxy‑7‑deazaguanine synthase QueE
RA 2,905,665 G→T D37Y (GAT→TAT)  yqcG → cell envelope stress response protein YqcG
RA 2,907,284 C→A A220S (GCT→TCT)  eno ← enolase
RA 2,910,067 G→T H207N (CAT→AAT)  mazG ← nucleoside triphosphate pyrophosphohydrolase
RA 2,914,360 G→T A214E (GCA→GAA)  rlmD ← 23S rRNA m(5)U1939 methyltransferase
RA 2,918,457 G→T P310Q (CCG→CAG)  gudD ← D‑glucarate dehydratase
RA 2,919,815 G→T A311D (GCC→GAC)  gudX ← glucarate dehydratase‑related protein
RA 2,923,153 G→T P211H (CCT→CAT)  truC ← tRNA pseudouridine(65) synthase
RA 2,942,008 G→T A187D (GCT→GAT)  gcvA ← DNA‑binding transcriptional dual regulator GcvA
RA 2,943,247 C→A intergenic (‑102/‑90) ygdI ← / → csdA DUF903 domain‑containing lipoprotein YgdI/cysteine sulfinate desulfinase
RA 2,949,209 C→A intergenic (‑199/‑33) amiC ← / → argA N‑acetylmuramoyl‑L‑alanine amidase C/N‑acetylglutamate synthase
RA 2,968,839 C→A E47* (GAG→TAG)  rppH ← RNA pyrophosphohydrolase
RA 2,970,684 G→T D89Y (GAT→TAT)  ygdQ → UPF0053 inner membrane protein YgdQ
RA 2,986,816 G→T G324C (GGT→TGT)  yqeG → putative transporter YqeG
RA 3,006,484 C→A R75S (CGC→AGC)  ygeW → putative carbamoyltransferase YgeW
RA 3,012,347 C→A A296E (GCG→GAG)  yqeA → putative amino acid kinase YqeA
RA 3,031,883 G→T G173C (GGT→TGT)  uacT → urate:H(+) symporter
RA 3,040,706 G→T P40T (CCG→ACG)  ygfX ← protein YgfX
RA 3,043,834 G→T G58V (GGA→GTA)  bglA → 6‑phospho‑beta‑glucosidase A
RA 3,043,887 G→T D76Y (GAC→TAC)  bglA → 6‑phospho‑beta‑glucosidase A
RA 3,054,283 G→T R186R (CGC→CGA)  pepP ← proline aminopeptidase P II
RA 3,054,775 G→T P22P (CCC→CCA)  pepP ← proline aminopeptidase P II
RA 3,059,554 G→T pseudogene (58/231 nt) yqfE ← conserved protein YqfE
RA 3,075,430 C→A E251D (GAG→GAT)  yggF ← fructose 1,6‑bisphosphatase YggF
RA 3,075,796 C→A A129A (GCG→GCT)  yggF ← fructose 1,6‑bisphosphatase YggF
RA 3,089,555 G→T L424L (CTG→CTT)  galP → galactose:H(+) symporter
RA 3,089,989 G→T E79* (GAA→TAA)  yggI → conserved protein YggI
RA 3,091,547 C→A A138A (GCC→GCA)  rsmE → 16S rRNA m(3)U1498 methyltransferase
RA 3,096,891 G→T G71C (GGT→TGT)  rdgB → dITP/XTP pyrophosphatase
RA 3,115,928 C→A G1062V (GGA→GTA)  yghJ ← putative lipoprotein YghJ
RA 3,118,935 G→C P60A (CCT→GCT)  yghJ ← putative lipoprotein YghJ
RA 3,122,299 G→T Q503K (CAA→AAA)  glcB ← malate synthase G
RA 3,139,723 C→A S81I (AGC→ATC)  hybG ← hydrogenase 2 accessory protein
RA 3,150,149 C→A A163E (GCG→GAG)  yghA → NADP(+)‑dependent aldehyde reductase
RA 3,156,876 C→A P85H (CCC→CAC)  dkgA → methylglyoxal reductase DkgA
RA 3,171,273 C→A L264I (CTC→ATC)  qseC → sensory histidine kinase QseC
RA 3,181,261 C→A P281T (CCG→ACG)  ygiC → putative enzyme with ATPase activity
RA 3,202,092 G→T G68C (GGT→TGT)  cca → fused tRNA nucleotidyltransferase/2',3'‑cyclic phosphodiesterase/2' nucleotidase and phosphatase
RA 3,217,945 G→T R378S (CGT→AGT)  aer ← aerotaxis sensor receptor, flavoprotein
RA 3,219,441 C→A intergenic (‑365/‑53) aer ← / → patA aerotaxis sensor receptor, flavoprotein/putrescine aminotransferase
RA 3,219,701 G→T A70S (GCG→TCG)  patA → putrescine aminotransferase
RA 3,227,142 G→T W303C (TGG→TGT)  ygjI → putative transporter YgjI
RA 3,231,072 C→A L729M (CTG→ATG)  ygjK → glycoside hydrolase
RA 3,232,088 G→T D142Y (GAC→TAC)  fadH → 2,4‑dienoyl‑CoA reductase
RA 3,243,481 G→T R421S (CGT→AGT)  uxaC ← D‑glucoronate/D‑galacturonate isomerase
RA 3,270,175 C→A intergenic (+573/+41) yhaC → / ← rnpB uncharacterized protein YhaC/RNase P catalytic RNA component
RA 3,270,969 C→A G268C (GGT→TGT)  garK ← glycerate 2‑kinase 1
RA 3,288,425 C→A A112A (GCC→GCA)  yraI → putative fimbrial chaperone YraI
RA 3,322,484 C→A V8F (GTT→TTT)  secG ← Sec translocon subunit SecG
RA 3,329,074 C→A L38M (CTG→ATG)  dacB → peptidoglycan DD‑endopeptidase DacB
RA 3,345,580 A→G E288E (GAA→GAG)  rpoN → RNA polymerase, sigma 54 (sigma N) factor
RA 3,348,103 C→A A46A (GCC→GCA)  npr → phosphorelay protein Npr
RA 3,352,163 G→T S288Y (TCC→TAC)  arcB ← sensory histidine kinase ArcB
RA 3,354,487 C→T intergenic (‑437/‑238) yhcC ← / → gltB radical SAM family oxidoreductase YhcC/glutamate synthase subunit GltB
RA 3,355,867 G→T Q381H (CAG→CAT)  gltB → glutamate synthase subunit GltB
RA 3,372,764 G→T R271R (CGC→CGA)  nanA ← N‑acetylneuraminate lyase
RA 3,381,551 G→T G270V (GGC→GTC)  degQ → periplasmic serine endoprotease
RA 3,384,473 G→T intergenic (‑205/‑230) mdh ← / → argR malate dehydrogenase/DNA‑binding transcriptional dual regulator ArgR
RA 3,408,306 C→A L234M (CTG→ATG)  panF → pantothenate:Na(+) symporter
RA 3,454,763 C→A E212D (GAG→GAT)  gspA ← Type II secretion system protein GspA
RA 3,465,252 G→T W57C (TGG→TGT)  gspM → Type II secretion system protein GspM
RA 3,469,513 G→T S114* (TCG→TAG)  chiA ← endochitinase
RA 3,479,030 C→A L526L (CTG→CTT)  kefB ← K(+) : H(+) antiporter KefB
RA 3,486,115 C→A intergenic (‑297/‑5) yhfA ← / → crp OsmC family protein/DNA‑binding transcriptional dual regulator CRP
RA 3,491,835 C→A G155C (GGC→TGC)  ppiA ← peptidyl‑prolyl cis‑trans isomerase A
RA 3,497,064 C→A A21E (GCA→GAA)  nirC → nitrite transporter NirC
RA 3,497,937 G→T R37L (CGC→CTC)  cysG → siroheme synthase
RA 3,499,372 C→A intergenic (+171/‑76) cysG → / → yhfL siroheme synthase/DUF4223 domain‑containing lipoprotein YhfL
RA 3,503,770 G→T D202Y (GAT→TAT)  frlD → fructoselysine 6‑kinase
RA 3,535,340 G→T L177M (CTG→ATG)  envZ ← sensory histidine kinase EnvZ
RA 3,541,735 G→T A443A (GCG→GCT)  feoB → Fe(2(+)) transporter FeoB
RA 3,545,026 C→A L49I (CTT→ATT)  yhgH → DNA utilization protein YhgH
RA 3,560,455 +G pseudogene (151/758 nt) glpR ← DNA‑binding transcriptional repressor GlpR
RA 3,573,232 G→T Q91K (CAG→AAG)  glgB ← 1,4‑alpha‑glucan branching enzyme
RA 3,580,541 C→A G89W (GGG→TGG)  yhhX ← putative oxidoreductase YhhX
RA 3,592,763 C→A L225L (CTG→CTT)  livF ← branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
RA 3,599,518 G→T T47T (ACC→ACA)  livJ ← branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein
RA 3,617,503 C→A I163I (ATC→ATA)  nikD → Ni(2(+)) ABC transporter ATP binding subunit NikD
RA 3,627,428 C→A R704L (CGC→CTC)  rbbA ← ribosome‑associated ATPase
RA 3,629,279 G→T P87Q (CCG→CAG)  rbbA ← ribosome‑associated ATPase
RA 3,645,155 C→A E10* (GAA→TAA)  prlC ← oligopeptidase A
RA 3,659,143 C→A intergenic (+61/‑89) gadF → / → mdtE small regulatory RNA GadF/multidrug efflux pump membrane fusion protein MdtE
RA 3,677,840 C→A G171W (GGG→TGG)  yhjG ← AsmA family protein YhjG
RA 3,686,554 G→T R874R (CGA→AGA)  bcsC ← cellulose biosynthesis protein BcsC
RA 3,698,989 C→A P259Q (CCA→CAA)  bcsG → cellulose phosphoethanolamine transferase
RA 3,708,293 C→A intergenic (‑588/+323) dppA ← / ← proK dipeptide ABC transporter periplasmic binding protein/tRNA‑Pro
RA 3,715,525 C→A A290A (GCG→GCT)  bisC ← biotin sulfoxide reductase
RA 3,719,142 C→A intergenic (‑98/‑336) yiaF ← / → yiaG DUF3053 domain‑containing protein YiaF/putative DNA‑binding transcriptional regulator YiaG
RA 3,739,739 G→T R12L (CGC→CTC)  avtA → valine‑‑pyruvate aminotransferase
RA 3,747,680 G→T L199L (CTG→CTT)  lyxK → L‑xylulose kinase
RA 3,754,492 C→A intergenic (‑64/+481) yiaW ← / ← aldB DUF3302 domain‑containing protein YiaW/aldehyde dehydrogenase B
RA 3,810,634 G→T S173R (AGC→AGA)  mutM ← DNA‑formamidopyrimidine glycosylase
RA 3,812,882 G→T S51I (AGC→ATC)  dfp → fused 4'‑phosphopantothenoylcysteine decarboxylase and phosphopantothenoylcysteine synthetase
RA 3,815,883 +C coding (667/687 nt) rph ← truncated RNase PH
RA 3,836,647 C→A intergenic (+331/‑306) selC → / → setC tRNA‑Sec/putative arabinose exporter
RA 3,852,821 G→T intergenic (‑37/+69) ilvB ← / ← ivbL acetohydroxy acid synthase I subunit IlvB/ilvBN operon leader peptide
RA 3,853,358 G→T intergenic (‑101/‑195) istR ← / → tisB small RNA IstR‑2/membrane‑depolarizing toxin TisB
RA 3,857,812 G→A T198I (ACC→ATC)  yidJ ← putative sulfatase/phosphatase
RA 3,889,637 G→T G303V (GGC→GTC)  tnaA → tryptophanase
RA 3,897,131 G→T G120C (GGC→TGC)  yieH → 6‑phosphogluconate phosphatase
RA 3,904,749 C→A Q283H (CAG→CAT)  bglF ← beta‑glucoside specific PTS enzyme II/BglG kinase/BglG phosphatase
RA 3,927,192 G→T S13I (AGC→ATC)  asnA → asparagine synthetase A
RA 3,934,676 G→T G300V (GGC→GTC)  rbsA → ribose ABC transporter ATP binding subunit
RA 3,939,909 C→A S235I (AGC→ATC)  hsrA ← putative transporter HsrA
RA 3,946,226 G→T noncoding (2523/2904 nt) rrlC → 23S ribosomal RNA
RA 3,951,284 C→A pseudogene (725/1645 nt) ilvG → acetolactate synthase II subunit IlvG, N‑terminal fragment (pseudogene)
RA 3,956,411 G→T G361W (GGG→TGG)  ilvA → threonine deaminase
RA 3,964,684 G→T A316D (GCC→GAC)  rhlB ← ATP‑dependent RNA helicase RhlB
RA 3,973,142 C→A N207K (AAC→AAA)  rffG → dTDP‑glucose 4,6‑dehydratase 2
RA 3,973,850 C→A P81P (CCC→CCA)  rffH → dTDP‑glucose pyrophosphorylase 2
RA 3,979,233 C→A F211L (TTC→TTA)  wzyE → enterobacterial common antigen polymerase
RA 3,995,635 G→T R18L (CGG→CTG)  yigA → conserved protein YigA
RA 4,007,741 C→A intergenic (+48/‑16) recQ → / → rhtC ATP‑dependent DNA helicase RecQ/L‑threonine exporter
RA 4,035,811 G→T noncoding (281/1542 nt) rrsA → 16S ribosomal RNA
RA 4,047,707 C→A Q248K (CAG→AAG)  polA → DNA polymerase I
RA 4,054,697 C→A A194A (GCG→GCT)  glnG ← DNA‑binding transcriptional dual regulator NtrC
RA 4,061,216 C→A P18T (CCT→ACT)  yihM → putative TIM barrel domain‑containing protein YihM
RA 4,069,904 C→A V166V (GTG→GTT)  yihR ← putative aldose 1‑epimerase YihR
RA 4,094,938 G→T L349M (CTG→ATG)  rhaA ← L‑rhamnose isomerase
RA 4,100,835 C→A P9Q (CCG→CAG)  sodA → superoxide dismutase (Mn)
RA 4,113,756 C→A P239P (CCG→CCT)  fpr ← flavodoxin/ferredoxin‑NADP(+) reductase
RA 4,133,316 G→T W234L (TGG→TTG)  metF → 5,10‑methylenetetrahydrofolate reductase
RA 4,138,141 G→T L299I (CTT→ATT)  gldA ← L‑1,2‑propanediol dehydrogenase/glycerol dehydrogenase
RA 4,141,196 C→A E342D (GAG→GAT)  ptsA ← putative PTS multiphosphoryl transfer protein PtsA
RA 4,150,741 C→A L786L (CTG→CTT)  ppc ← phosphoenolpyruvate carboxylase
RA 4,175,375 C→A intergenic (‑349/‑13) coaA ← / → thrU pantothenate kinase/tRNA‑Thr
RA 4,183,798 G→T A852S (GCT→TCT)  rpoB → RNA polymerase subunit beta
RA 4,194,194 G→T P4H (CCT→CAT)  thiE ← thiamine phosphate synthase
RA 4,225,958 G→T G711W (GGG→TGG)  metH → cobalamin‑dependent methionine synthase
RA 4,261,710 C→A S14R (AGC→AGA)  dusA → tRNA‑dihydrouridine synthase A
RA 4,263,253 G→T P327T (CCA→ACA)  qorA ← putative quinone oxidoreductase 1
RA 4,265,940 C→T D53D (GAC→GAT)  alr → alanine racemase 1
RA 4,270,342 C→A I35I (ATC→ATA)  yjbQ → UPF0047 protein YjbQ
RA 4,279,933 C→G intergenic (+105/‑47) ghxP → / → yjcE guanine/hypoxanthine transporter GhxP/putative transporter YjcE
RA 4,296,381 +GC intergenic (+587/+55) gltP → / ← yjcO glutamate/aspartate : H(+) symporter GltP/Sel1 repeat‑containing protein YjcO
RA 4,309,977 G→T A335D (GCC→GAC)  alsA ← D‑allose ABC transporter ATP binding subunit
RA 4,320,740 G→T L170I (CTC→ATC)  phnH ← carbon‑phosphorus lyase core complex subunit PhnH
RA 4,324,701 G→T G155G (GGC→GGA)  phnC ← phosphonate ABC transporter ATP binding subunit
RA 4,326,253 C→A intergenic (‑512/+146) yjdN ← / ← yjdM conserved protein YjdN/conserved protein YjdM
RA 4,337,675 C→A T85T (ACG→ACT)  adiY ← DNA‑binding transcriptional activator AdiY
RA 4,356,412 G→T intergenic (‑1/+58) dtpC ← / ← cadA dipeptide/tripeptide:H(+) symporter DtpC/lysine decarboxylase 1
RA 4,358,521 T→C I33V (ATT→GTT)  cadA ← lysine decarboxylase 1
RA 4,361,266 C→A V223V (GTG→GTT)  cadC ← DNA‑binding transcriptional activator CadC
RA 4,362,098 G→T intergenic (‑164/+453) cadC ← / ← pheU DNA‑binding transcriptional activator CadC/tRNA‑Phe
RA 4,364,660 C→A C128F (TGT→TTT)  dsbD ← protein disulfide oxidoreductase ‑ DsbDreduced
RA 4,364,787 C→A E86* (GAA→TAA)  dsbD ← protein disulfide oxidoreductase ‑ DsbDreduced
RA 4,372,597 C→A P525T (CCG→ACG)  groL → chaperonin GroEL
RA 4,381,573 C→A R249L (CGC→CTC)  frdA ← fumarate reductase flavoprotein subunit
RA 4,383,500 C→A A286A (GCC→GCA)  epmA → EF‑P‑lysine lysyltransferase
RA 4,387,485 A→C L629R (CTG→CGG)  mscM ← miniconductance mechanosensitive channel MscM
RA 4,426,293 G→T L62L (CTG→CTT)  rplI → 50S ribosomal subunit protein L9
RA 4,456,746 C→A A321E (GCG→GAG)  mpl → UDP‑N‑acetylmuramate‑‑L‑alanyl‑gamma‑D‑glutamyl‑ meso‑2,6‑diaminoheptanedioate ligase
RA 4,472,141 C→A K85N (AAG→AAT)  pyrB ← aspartate carbamoyltransferase catalytic subunit
RA 4,476,042 G→T Q202H (CAG→CAT)  yjgL → protein YjgL
RA 4,486,033 C→A intergenic (‑82/‑185) pepA ← / → lptF aminopeptidase A/I/lipopolysaccharide transport system protein LptF
RA 4,502,521 C→A G304V (GGG→GTG)  insG ← KpLE2 phage‑like element; IS4 putative transposase
RA 4,509,976 G→T pseudogene (173/330 nt) yjhV → KpLE2 phage‑like element; putative uncharacterized protein YjhV
RA 4,512,019 G→T T132T (ACC→ACA)  fecD ← ferric citrate ABC transporter membrane subunit FecD
RA 4,512,726 G→T A228A (GCC→GCA)  fecC ← ferric citrate ABC transporter membrane subunit FecC
RA 4,516,311 C→A G123C (GGT→TGT)  fecA ← ferric citrate outer membrane transporter
RA 4,527,038 C→A W167L (TGG→TTG)  sgcE ← KpLE2 phage‑like element; putative epimerase SgcE
RA 4,535,268 C→A pseudogene (254/1017 nt) yjhR → KpLE2 phage‑like element; PLD‑like domain‑containing protein YjhR
RA 4,535,443 C→A pseudogene (429/1017 nt) yjhR → KpLE2 phage‑like element; PLD‑like domain‑containing protein YjhR
RA 4,560,434 C→A A83S (GCG→TCG)  yjiH ← Gate family protein YjiH
RA 4,571,472 C→A E35* (GAG→TAG)  yjiR ← fused putative DNA‑binding transcriptional regulator/putative aminotransferase YjiR
RA 4,582,005 C→A Q348H (CAG→CAT)  hsdM ← type I restriction enzyme EcoKI methyltransferase component
RA 4,592,967 C→A S437R (AGC→AGA)  tsr → methyl‑accepting chemotaxis protein Tsr
RA 4,606,224 C→A noncoding (63/87 nt) leuP ← tRNA‑Leu
RA 4,617,658 G→T A112A (GCG→GCT)  deoC → deoxyribose‑phosphate aldolase

Unassigned missing coverage evidence
   seq id start end size ←reads reads→ gene description
* * ÷ NC_000913 1196270 1211433 15164 39 [34] [34] 39 [icd]–[icdC] [icd],ymfD,ymfE,lit,intE,xisE,ymfH,ymfI,ymfJ,ymfK,ymfT,ymfL,ymfM,oweE,ymfN,aaaE,ymfR,beeE,jayE,ymfQ,ycfK,tfaP,tfaE,stfE,pinE,mcrA,[icdC]
* * ÷ NC_000913 3102949 3104052 1104 37 [34] [36] 37 [mutY] [mutY]
* * ÷ NC_000913 3423770–3424234 3424538–3424240 7–769 40 [35] [36] 38 [rrfD]–[rrlD] [rrfD],[rrlD]

Unassigned new junction evidence
  seq id position reads (cov) reads (cov) score skew freq annotation gene product
* ? NC_000913 = 12994980 (0.000)181 (1.460) 94/270 0.0 100% intergenic (+253/‑33) ychE/insH21 putative inner membrane protein/IS5 transposase and trans‑activator
?NC_000913 1300698 = 0 (0.000)intergenic (+151/‑484) insH21/oppA IS5 transposase and trans‑activator/oligopeptide ABC transporter periplasmic binding protein
* ? NC_000913 3363001 =219 (1.720)174 (1.370) 78/276 0.1 61.0% coding (195/2382 nt) yhcD putative fimbrial usher protein YhcD
?NC_000913 3766087 = 5 (0.040)coding (3905/4134 nt) rhsA rhs element protein RhsA
* ? NC_000913 = 3653230NA (NA)146 (1.140) 75/278 0.1 94.2% noncoding (1/1195 nt) IS5 repeat region
?NC_000913 = 3766089 9 (0.070)coding (3907/4134 nt) rhsA rhs element protein RhsA
* ? NC_000913 4542682 =95 (0.740)37 (0.310) 29/260 2.3 27.4% intergenic (+49/‑433) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
?NC_000913 4542996 = 107 (0.900)intergenic (+363/‑119) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
* ? NC_000913 = 454269095 (0.740)38 (0.320) 26/260 2.6 28.0% intergenic (+57/‑425) fimE/fimA regulator for fimA/type 1 fimbriae major subunit
?NC_000913 = 4542986 107 (0.900)intergenic (+353/‑129) fimE/fimA regulator for fimA/type 1 fimbriae major subunit