Intuitive matrices for microbial mutation data

High quality curated mutations from related samples in organized, interactive and annotated tables

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Want to see your unpublished/private mutations on ALEDB?

Snapshot of a mutation table

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Mutation Type	Observed Mutations	Unique Mutations
Single Base Substitutions	2293586	873973
Multiple Base Substitutions	135378	45975
Deletions	118199	26635
Insertions	121327	21381
Mobile Element Insertions	9303	1563
Amplifications	46023	36504
Gene Conversions	17	5
Inversions	6	1

ALEDB is the largest collection of microbial evolution mutation data in the world

2723839 instances of 1006037 unique mutations from 13232 isolates across 268 unique projects

More projects added every month

Search through ALEDB to compare results from multiple experiments at once

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When logged in, search will also include private projects you have access to as well

Three mutation callers for triple the confidence

Industry standard tools Breseq and GATK's HaplotypeCaller for more standard mutation calls

CNVnator for larger deletions and amplification mutations

Detailed alignment and coverage reports powered by gdtools for a consistent browsing experience

Example mutation alignment reports: SNP, INS, AMP

Easily export mutation data as CSV spreadsheets

For further analysis using your favorite spreadsheet tools and scripts

Click here for an example export download

ALEDB contains data from over 93 different publications from around the world

To add your own data on ALEDB or to run your own ALE experiment
contact us here

License

ALEDB is released under the MIT License. Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE, OR OTHERWISE ARISING FROM THE USE OR OTHER DEALINGS IN THE SOFTWARE.

ALEDB is hosted and maintained by the Systems Biology Research Group at the University of California, San Diego.